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Changing Haemophilia®

With Changing Haemophilia® we address the unmet needs in haemophilia and other rare blood disorders. Together with you and our community partners we are striving for better access to care, diagnosis and multidisciplinary care.
Rare Disease

For people living with a rare disease, the lack of awareness and treatment options can make the entire experience extremely challenging and uncertain. Though each rare disease is complex and challenging to diagnose and manage, they do share many commonalities.

Resources for treaters of rare bleeding disorders. Here you can find information and resources around haemophilia and in rare blood disorders.

WFH 2024

On April 21-24th 2024 The World Federation of Hemophilia (WFH) and La Federación Española de Hemofilia (Fedhemo) will welcome you to the global bleeding disorders community at WFH 2024 World Congress in Madrid, Spain.

Haemophilia Esperoct

Esperoct® offers patients with haemophilia A a treatment tailored to their needs with higher FVIII activity levels and low ABR allowing them to move beyond the conventional limitations of haemophilia A1-4.
Haemophilia Refixia

Refixia® is an extended half-life recombinant FIX used in routine prophylaxis as well as for bleed control and surgical procedure for HB patients5. Refixia® once weekly prophylaxis gives your patient the confidence to live beyond haemophilia B maintaining high FIX activity level in the non-haemophilia range most of the time5-9.
Haemophilia Inhibitors

Over 30 years of research and clinical experience NovoSeven® supporting your patients in more indications than any other bypassing agent.
NovoSeven® for severe postpartum hemorrhage when uterotonics are not sufficient to stop the bleed10-14.

1.

Esperoct® Summary of Product Characteristics, 2020.

2.

Chowdary P et al. Res Pract Thromb Haemost 2019; 3:542–554.

3.

Giangrande P et al. J Thromb Haemost 2017; 117:252–261.

4.

Giangrande P et al. J Thromb Haemost 2020; 18:5–14

5.

Refixia® Summary of Product Characteristics, 2022.

6.

Collins PW et al. Blood 2014; 124:3880–3886.

7.

Negrier C et al. Haemophilia 2016; 22:507–513.

8.

Tiede A et al. Haemophilia 2017; 23:547–555.

9.

Young G et al. Thromb Res 2016; 141:69–76.

10.

NovoSeven® Summary of Product Characteristics, accessed: Jan 2023.

11.

Hedner, 2015, Blood Reviews

12.

FEIBA 500 U Summary of Product Characteristics, Jan 2016

13.

Obizur EMA Summary of Product Characteristics, April 2022

14.

Hemlibra Summary of Product Characteristics, Sep 2022